Fentanyl is The
#1 Killer of Americans
18 to 45
Cessation is developing novel antibody therapies to prevent and reverse overdose related to fentanyl and fentanyl analogs
Fentanyl kills more Americans annually
than breast cancer and
HIV/AIDS at its peak.
-Centers for Disease Control and Prevention
“Fentanyl is the single greatest
challenge the US faces
as a country.”
-Alejandro Mayorkas, U.S. Dept of Homeland Security
Fentanyl Deaths Per Year
United States
No Data Found
0
+
Americans died from from fentanyl overdose in 2022. That's 180 people every day
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Fentanyl Program
Preclinical
CMC & Tox
Phase I
Phase II
Fentanyl Overdose Prevention
CSX-1004 IV (mAb infusion)
Fentanyl Overdose Prevention
CSX-1004 SQ (mAb subcutaneous)
Rapid Fentanyl Overdose Reversal
CSX-1100 (scFv auto-injector)
Admiral James “Sandy” Winnefeld
"As a Navy admiral, I helped lead one of the most powerful militaries in the world. Today, our nation is confronting a deadly crisis right here at home. Fentanyl is highly potent, exceedingly addictive, and extraordinarily dangerous, and can easily kill someone the first time they use it, whether intentionally or inadvertently. That's why innovative ways to protect our population from this drug are so important . . . and it's also why, on a purely volunteer basis, I'm helping Cessation advance an extremely promising tool in our effort to overcome this epidemic."
"The introduction of fentanyl to the substance use disorder crisis has had a deadly and devastating impact…. Throughout the United States, we have a generation of grandparents who are raising their grandchildren. And for some, it’s because parents were separated from kids due to their addiction. But tragically for others, it’s because parents did not survive their addiction. Now, with the rise of social media, we’re seeing another younger generation become more vulnerable than ever to marketing of these drugs and to the increased accessibility that that means, everything must be done to stop the next generation from succumbing to this epidemic."
Senator Jeanne Shaheen (D-NH)
Rep. Brett Guthrie (R-KY)
"Over the past several years, the United States has seen historic rise of drug overdoses driven by an increased supply of synthetic opioids, such as illicit fentanyl analogs.… You cannot go a week without reading or hearing about the stories of mothers, sons, sisters, brothers and shares, friends and even babies losing their lives to fentanyl overdoses. How could this be possible?"
Tracy M. Woody
Paul Bremer, Ph.D.
Andrew C. Barrett, Ph.D.
Nicholas Jacob, Ph.D.
Our team
- Tracy - President & Chief Executive Officer
- Andrew - Chief Scientific Officer
- Paul - Research and Development Director
- Nicholas - Senior Research Scientist
